Anusol Suppositories provide targeted soothing relief from the discomfort of internal piles (hemorrhoids), fissures and anal itching. They contain active ingredients that soothe itching, shrink piles and prevent bacterial growth which can promote healing. Directions for use: Topical use only. Insert one suppository into the back passage at night, in the morning and after each bowel movement. Not recommended for children. If symptoms persist consult your doctor. If you are pregnant or breastfeeding, only use this medicine on the advice of your doctor.